We will discuss the use of a porcine model of pediatric traumatic brain injury, with a particular focus of bioenergetic dysfunction following injury and the use of mitochondrial targeted therapies to reduce injury.  In addition, we will discuss the use of state of the art neuromonitoring (cerebral blood flow, microdialysis, tissue therapies, and the development of a state of the art porcine intensive care unit, mimicking the Children's Hospital of Philadelphia's pediatric neurocritical care unit.

Bio:  Todd J. Kilbaugh, M.D.

Dr. Kilbaugh is an Assistant Professor of Anesthesiology, Critical Care Medicine, Nursing, and Pediatrics and Pediatric Critical Care Medicine at The University of Pennsylvania School of Medicine and the Children's Hospital of Philadelphia.  He is board certified in Pediatrics, Pediatric Critical Care, Anesthesiology, Pediatric Anesthesiology, and Pediatric Cardiac Anesthesiology.  Dr. Kilbaugh is an attending physician in the pediatric critical care unit as well as the operating rooms, and has considerable experience with peri-operative critically ill patients.  As a clinician scientist he has extensive experience using a translational immature porcine model of traumatic brain injury (focal and diffuse) to study mitochondrial-targeted neuroprotection as well as development of porcine neurocritical care; including various modes of intracranial monitoring and imaging.