David DeOrnellis, BS, RLATg, CPIA, CM
Revisiting Guinea Pig Biomethodology: What is effective and appropriate?
The introduction of Guinea pigs to our facility prompted the Laboratory Animal Services (LAS) training team at the Novartis Institutes for BioMedical Research in Cambridge, MA (NIBR Cambridge), to research common research techniques (handling, restraint, anesthesia, compound administration, blood collection, euthanasia, etc.) for implementation. Despite being an established research model, Guinea pig biomethodology continues to be limited and, in some cases, thought to be challenging. After extensive literature review and collaborations with industry colleagues, there appears to be a wide range of opinion and conflicting information regarding appropriate Guinea pig biomethodology. Our skilled training team set out to evaluate and define optimal techniques, ensuring data/sample quality and humane animal welfare standards. This lecture will describe our experience in successfully implementing the Guinea pig as a research model at our facility.
David DeOrnellis is the Associate Director of Technical Services for the Laboratory Animal Services (LAS) department at the Novartis Institutes for BioMedical Research in Cambridge, MA, where he leads a centralized team responsible for in vivo study and surgical support, training, and colony management. He has recently collaborated with the AALAS Educational Resources Committee in the publication of Techniques Training: Mouse and Techniques Training: Rat, valuable training resources related to in vivo technical procedures.